4SC provides Q3 highlights and financial forecast

Key highlights of Q3 2021

* 185 patients were enrolled into the pivotal RESMAIN study
* 18 patients were enrolled into the pivotal MERKLIN 2 study
* The first patients were recruited into the TURANDOT study
* Data from the DONIMI study was presented at the ESMO Congress of the European Society of Medical Oncology

Cash balance development in Q3 2021 and financial forecast

As of 30 September 2021, 4SC holds cash balance/funds of €32,381 thousand as compared to €36,545 thousand as of 30 June 2021.

The average monthly use of cash from operations amounted to €918 thousand on average in the first nine months of 2021 (9M 2020: €1,172 thousand). Excluding the cash contribution received from the transaction with Immunic signed in Q1 2021, the average monthly use of cash from operating activities was €1,731 thousand.

The decrease of cash funds in the first nine months of 2021 is mainly a result of the expenditures for the ongoing clinical study RESMAIN as well as for the expansion of the clinical program for domatinostat, particularly in MCC.

Based on current financial and operating activities and taking into account the additional funds provided by the settlement agreement with Immunic in the first half-year 2021, the Manage­ment Board of 4SC estimates that current funds should be sufficient to finance 4SC into the second half of 2022.

Forward-looking information

Information set forth in this press release contains forward-looking statements, which involve risks and uncertainties. The forward-looking statements contained herein represent the judgement of 4SC as of the date of this press release. Such forward-looking statements are neither promises nor guarantees but are subject to a variety of risks and uncertainties, many of which are beyond 4SC’s control, and which could cause actual results to differ materially from those contemplated in these forward-looking statements. 4SC expressly disclaims any obligation or undertaking to release any updates or revisions to any such statements to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based.